Bronchial Hyperreactivity in the Peripheral Airways.
نویسندگان
چکیده
منابع مشابه
Evaluation of the Effect of Onosma Bracteatum Wall (Boraginaceae) On Bronchial Hyperreactivity in Sensitized Guinea Pigs
Asthma is a chronic inflammatory disorder of the airways. The available treatment options have major limitations owing to low efficacy, associated adverse events and compliance issues. Therefore, the health burden of bronchial asthma is increasing globally at an alarming rate, providing a strong impetus for the development of new therapeutics. Onosma bracteatum ( O. bracteatum ) is know...
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Asthma is a chronic disease characterized by increased bronchial responsiveness ranging in degree from mild ~o severe. AU:Way inflammation has been receiving 1ncrcased auenuon as the major mechanism in bronchial hypcrrcsponsiveness. Many stimuli known to induce airwa~ inflam~ation ~lso i.ncrease bronchial reactivity, e.g. v~ral rcsp1ratory mfectJOns, ozone, antigens and chem1ca ls such as tolue...
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BACKGROUND Antibody deficiency comprises a heterogeneous group of disorders characterised by the body's inability to mount an effective antibody response to pathogens. Although it has been reported that asthma and allergic disease are frequent in antibody deficiencies, there are no data that evaluate and compare bronchial hyperreactivity (BHR) in all groups of antibody deficiencies. In this stu...
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This report examines the effect of an anti-VLA-4 monoclonal antibody (mAb) HP1/2 on antigen-induced bronchial hyperreactivity to methacholine, and on eosinophil and T lymphocyte infiltration in the airways of guinea pigs sensitized and challenged by aerosolized ovalbumin and used 24 h thereafter. The intravenous administration of 2.5 mg/kg of HP1/2, but not of its isotype-matched mAb 1E6, 1 h b...
متن کاملAssociation of insulin resistance with bronchial hyperreactivity
BACKGROUND Several epidemiologic studies showed the significant association of insulin resistance with asthma. OBJECTIVE The aim of this study was to evaluate the association of insulin resistance with airway hyperresponsiveness (AHR) in adult population. METHODS 1,058 subjects who visited to the Seoul National University Hospital Gangnam Center from October 2007 to January 2009 for a routi...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1995
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.175.143